Neurodegenerative Diseases and Stem Cell Transplantation
نویسندگان
چکیده
منابع مشابه
Neurodegenerative Diseases and Stem Cell Transplantation
Abbreviations: AD: Alzheimer’s Disease; ASCs: Adult Stem Cells; BDNF: Brain Derived Neurotrophic Factor; CNS: Central Nervous System; ESCs: Embryonic Stem Cells; FGF-2: Fibroblast Growth Factor 2: HD: Huntington’s Disease; HSCs: Haematopoietic Stem Cells; IBMX: 3-Isobutyl-1-methylxanthine; L-DOPA: L-dihydroxyphenyl alanine; MPTP: 1-methyl-4phenyl-1, 2,3,6 tetrahydropyridine; MS: Multiple Sclero...
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Neurodegenerative diseases, amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar degeneration (FTLD), Huntington’s disease (HD), and multiple sclerosis (MS), are characterized by progressive degeneration of particular neuronal cells. Neurodegenerative disorders are believed to share a common pathophysiologic mechanism that allows the depo...
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002 drugs against AD [7]. Bone marrow-derived mesenchymal stem cells (MSCs) were able to home on the injured brain and remove Abeta plaques from the hippocampus and to reduce Abeta deposits through the activation of endogenous microglia in an induced AD mouse model [8]. Human umbilical cord-derived MSCs have been shown to improve memory deficits, and reduce Abeta deposition [9]. Moreover, one r...
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The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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ژورنال
عنوان ژورنال: Journal of Stem Cell Research & Therapy
سال: 2015
ISSN: 2157-7633
DOI: 10.4172/2157-7633.1000277